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Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

Phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α) on serine 51 integrates general translation repression with activation of stress-inducible genes such as ATF4, CHOP, and BiP in the unfolded protein response. We sought to identify new genes active in this phospho...

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Hlavní autoři: Novoa, Isabel, Zeng, Huiqing, Harding, Heather P., Ron, David
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174339/
https://ncbi.nlm.nih.gov/pubmed/11381086
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