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Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inducer of cancer cell death that holds promise in cancer therapy. Cancer cells are more susceptible than normal cells to the cell-death-inducing effects of TRAIL. However, a variety of cancer cells are resistant to TRAIL through...

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Main Authors: Teng, Y, Gao, M, Wang, J, Kong, Q, Hua, H, Luo, T, Jiang, Y
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944242/
https://ncbi.nlm.nih.gov/pubmed/24525736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.24
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