Tunicamycin enhances TRAIL-induced apoptosis by inhibition of cyclin D1 and the subsequent downregulation of survivin

TNF-related apoptosis-inducing ligand (TRAIL) has been proposed as a promising cancer therapy that preferentially induces apoptosis in cancer cells, but not most normal tissues. However, many cancers are resistant to TRAIL by mechanisms that are poorly understood. In this study, we showed that tunic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Hai-Yan, Du, Zhen-Xian, Liu, Bao-Qin, Gao, Yan-Yan, Meng, Xin, Guan, Yifu, Deng, Wei-Wei, Wang, Hua-Qin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society of Medical Biochemistry and Molecular Biology 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701986/
https://ncbi.nlm.nih.gov/pubmed/19307757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.5.041
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