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Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin’s lymphoma B cells

BACKGROUND: Non-Hodgkin's B-cell lymphomas account for approximately 70% of B-cell lymphomas. While its incidence is dramatically increasing worldwide, the disease is still associated with high morbidity due to ineffectiveness of conventional therapies, creating an urgent need for novel therape...

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Detalhes bibliográficos
Main Authors: Jacquemin, Guillaume, Granci, Virginie, Gallouet, Anne Sophie, Lalaoui, Najoua, Morlé, Aymeric, Iessi, Elisabetta, Morizot, Alexandre, Garrido, Carmen, Guillaudeux, Thierry, Micheau, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248929/
https://ncbi.nlm.nih.gov/pubmed/21933852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.046466
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