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Tunicamycin enhances TRAIL-induced apoptosis by inhibition of cyclin D1 and the subsequent downregulation of survivin

TNF-related apoptosis-inducing ligand (TRAIL) has been proposed as a promising cancer therapy that preferentially induces apoptosis in cancer cells, but not most normal tissues. However, many cancers are resistant to TRAIL by mechanisms that are poorly understood. In this study, we showed that tunic...

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Detalhes bibliográficos
Main Authors: Zhang, Hai-Yan, Du, Zhen-Xian, Liu, Bao-Qin, Gao, Yan-Yan, Meng, Xin, Guan, Yifu, Deng, Wei-Wei, Wang, Hua-Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Medical Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701986/
https://ncbi.nlm.nih.gov/pubmed/19307757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.5.041
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