CELL SURFACE COMPLEMENT REGULATORS MODERATE EXPERIMENTAL MYASTHENIA GRAVIS PATHOLOGY

Por KUSNER, LINDA L., HALPERIN, JOSE A., KAMINSKI, HENRY J.
Publicado no Muscle Nerve (2012)

A distinctive histidine residue is essential for in vivo glycation-inactivation of human CD59 transgenically expressed in mice erythrocytes: Implications for human diabetes complic...

Por Sahoo, Rupam, Ghosh, Pamela, Chorev, Michael, Halperin, Jose A
Publicado no Am J Hematol (2017)

Role of Complement and Complement Regulatory Proteins in the Complications of Diabetes

Por Ghosh, Pamela, Sahoo, Rupam, Vaidya, Anand, Chorev, Michael, Halperin, Jose A.
Publicado no Endocr Rev (2015)

Depletion of eIF2.GTP.Met-tRNA(i) translation initiation complex up-regulates BRCA1 expression in vitro and in vivo

Por Aktas, Bertal H., Bordelois, Paula, Peker, Selen, Merajver, Sophia, Halperin, Jose A.
Publicado no Oncotarget (2015)

Synthetic studies towards aryl-(4-aryl-4H-[1,2,4]triazole-3-yl)-amine from 1,3-diarylthiourea as urea mimetics

Por Natarajan, Amarnath, Guo, Yuhong, Arthanari, Haribabu, Wagner, Gerhard, Halperin, Jose A., Chorev, Michael
Publicado em 2005

Depletion of intracellular Ca(2+) stores, phosphorylation of eIF2α, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole

Por Aktas, Huseyin, Flückiger, Rudolf, Acosta, Juan A., Savage, Joyce M., Palakurthi, Sangeetha S., Halperin, José A.
Publicado em 1998

Deficiency of the Complement Regulatory Protein CD59 Accelerates the Development of Diabetes-induced Atherosclerosis in Mice

Por Liu, Fengming, Sahoo, Rupam, Ge, Xiaowen, Wu, Lin, Ghosh, Pamela, Qin, Xuebin, Halperin, Jose A.
Publicado no J Diabetes Complications (2016)

Plasma Glycated CD59 Predicts Early Gestational Diabetes and Large for Gestational Age Newborns

Por Ma, DongDong, Luque-Fernandez, Miguel Angel, Bogdanet, Delia, Desoye, Gernot, Dunne, Fidelma, Halperin, Jose A
Publicado no J Clin Endocrinol Metab (2020)

Glycation of the Complement Regulatory Protein CD59 Is a Novel Biomarker for Glucose Handling in Humans

Por Ghosh, Pamela, Vaidya, Anand, Sahoo, Rupam, Goldfine, Allison, Herring, Neil, Bry, Lynn, Chorev, Michael, Halperin, Jose A.
Publicado em 2014

Emerging Protein Biomarkers for the Diagnosis or Prediction of Gestational Diabetes—A Scoping Review

Por Bogdanet, Delia, Reddin, Catriona, Murphy, Dearbhla, Doheny, Helen C., Halperin, Jose A., Dunne, Fidelma, O’Shea, Paula M.
Publicado no J Clin Med (2021)

3-Substituted Indazoles as Configurationally Locked 4EGI-1 Mimetic and Inhibitors of eIF4E/eIF4G Interaction

Por Yefidoff-Freedman, Revital, Chen, Ting, Sahoo, Rupam, Chen, Limo, Wagner, Gerhard, Halperin, Jose A., Aktas, Bertal H., Chorev, Michael
Publicado no Chembiochem (2014)

A High-Affinity Inhibitor of Human CD59 Enhances Complement-Mediated Virolysis of HIV-1: Implications for Treatment of HIV-1/AIDS

Por Hu, Weiguo, Yu, Qigui, Hu, Ningjie, Byrd, Daniel, Amet, Tohti, Shikuma, Cecilia, Shiramizu, Bruce, Halperin, Jose A., Qin, Xuebin
Publicado no J Immunol (2009)

Generation and phenotyping of mCd59a and mCd59b double-knockout mice

Por Qin, Xuebin, Hu, Weiguo, Song, Wenping, Grubissich, Luciano, Hu, Xuemei, Wu, Gongxiong, Ferris, Sean, Dobarro, Martin, Halperin, Jose A.
Publicado no Am J Hematol (2009)

Complement regulator CD59 protects against angiotensin II-induced abdominal aortic aneurysms in mice

Por Wu, Gongxiong, Chen, Ting, Shahsafaei, Aliakbar, Hu, Weiguo, Bronson, Rod T., Shi, Guo-Ping, Halperin, Jose A, Aktas, Huseyin, Qin, Xuebin
Publicado em 2010

Small-molecule targeting of translation initiation for cancer therapy

Por Aktas, Bertal H., Qiao, Yuan, Ozdelen, Esra, Schubert, Roland, Sevinc, Sema, Harbinski, Fred, Grubissich, Luciano, Singer, Samuel, Halperin, Jose A.
Publicado em 2013

The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model

Por Hu, Weiguo, Jin, Richard, Zhang, Jinyan, You, Tao, Peng, Zhihai, Ge, Xiaowen, Bronson, Roderick T., Halperin, Jose A., Loscalzo, Joseph, Qin, Xuebin
Publicado em 2010

A Specific And Sensitive Assay For Blood Levels Of Glycated Cd59: A Novel Biomarker For Diabetes

Por Ghosh, Pamela, Sahoo, Rupam, Vaidya, Anand, Cantel, Sonia, Kavishwar, Amol, Goldfine, Allison, Herring, Neil, Bry, Lynn, Chorev, Michael, Halperin, Jose A.
Publicado em 2013

Synthesis of Rigidified eIF4E/eIF4G Inhibitor-1 (4EGI-1) Mimetic and Their in Vitro Characterization as Inhibitors of Protein–Protein Interaction

Por Mahalingam, Poornachandran, Takrouri, Khuloud, Chen, Ting, Sahoo, Rupam, Papadopoulos, Evangelos, Chen, Limo, Wagner, Gerhard, Aktas, Bertal H., Halperin, Jose A., Chorev, Michael
Publicado em 2014

Structure-activity relationship study of 4EGI-1, small molecule eIF4E/eIF4G protein-protein interaction inhibitors

Por Takrouri, Khuloud, Chen, Ting, Papadopoulos, Evangelos, Sahoo, Rupam, Kabha, Eihab, Chen, Han, Cantel, Sonia, Wagner, Gerhard, Halperin, Jose A, Aktas, Bertal H, Chorev, Michael
Publicado em 2014

Balancing role of nitric oxide in complement-mediated activation of platelets from mCd59a and mCd59b double-knockout mice

Por Qin, Xuebin, Hu, Weiguo, Song, Wenping, Blair, Price, Wu, Gongxiong, Hu, Xuemei, Song, Yanli, Bauer, Selena, Feelisch, Martin, Leopold, Jane A., Loscalzo, Joseph, Halperin, Jose A.
Publicado no Am J Hematol (2009)