Balancing role of nitric oxide in complement-mediated activation of platelets from mCd59a and mCd59b double-knockout mice

CD59 is a membrane protein inhibitor of the membrane attack complex (MAC) of complement. mCd59 knockout mice reportedly exhibit hemolytic anemia and platelet activation. This phenotype is comparable to the human hemolytic anemia known as paroxysmal nocturnal hemoglobinuria (PNH), in which platelet a...

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Bibliografiset tiedot
Julkaisussa:Am J Hematol
Päätekijät: Qin, Xuebin, Hu, Weiguo, Song, Wenping, Blair, Price, Wu, Gongxiong, Hu, Xuemei, Song, Yanli, Bauer, Selena, Feelisch, Martin, Leopold, Jane A., Loscalzo, Joseph, Halperin, Jose A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280257/
https://ncbi.nlm.nih.gov/pubmed/19229985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21363
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