Generation and phenotyping of mCd59a and mCd59b double-knockout mice

CD59 is a membrane protein inhibitor of the membrane attack complex (MAC) of complement. Humans express only one, whereas mice express two CD59 genes. We previously reported the targeted deletion of the mCd59b gene in which absence of mCd59b together with an unintended down regulation of mCd59a caus...

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Bibliografische gegevens
Gepubliceerd in:Am J Hematol
Hoofdauteurs: Qin, Xuebin, Hu, Weiguo, Song, Wenping, Grubissich, Luciano, Hu, Xuemei, Wu, Gongxiong, Ferris, Sean, Dobarro, Martin, Halperin, Jose A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280255/
https://ncbi.nlm.nih.gov/pubmed/19051264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21319
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