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Generation and phenotyping of mCd59a and mCd59b double-knockout mice

CD59 is a membrane protein inhibitor of the membrane attack complex (MAC) of complement. Humans express only one, whereas mice express two CD59 genes. We previously reported the targeted deletion of the mCd59b gene in which absence of mCd59b together with an unintended down regulation of mCd59a caus...

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Publicat a:Am J Hematol
Autors principals: Qin, Xuebin, Hu, Weiguo, Song, Wenping, Grubissich, Luciano, Hu, Xuemei, Wu, Gongxiong, Ferris, Sean, Dobarro, Martin, Halperin, Jose A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280255/
https://ncbi.nlm.nih.gov/pubmed/19051264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21319
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