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Application of a novel inhibitor of human CD59 for the enhancement of complement-dependent cytolysis on cancer cells
Many monoclonal antibodies (mAbs) have been extensively used in the clinic, such as rituximab to treat lymphoma. However, resistance and non-responsiveness to mAb treatment have been challenging for this line of therapy. Complement is one of the main mediators of antibody-based cancer therapy via th...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003131/ https://ncbi.nlm.nih.gov/pubmed/21258360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2010.35 |
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