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A High-Affinity Inhibitor of Human CD59 Enhances Complement-Mediated Virolysis of HIV-1: Implications for Treatment of HIV-1/AIDS

Many pathogenic enveloped viruses, including HIV-1, escape complement-mediated virolysis by incorporating host cell regulators of complement activation into their own viral envelope. The presence of complement regulators including CD59 on the external surface of the viral envelope confers resistance...

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Библиографические подробности
Опубликовано в: :J Immunol
Главные авторы: Hu, Weiguo, Yu, Qigui, Hu, Ningjie, Byrd, Daniel, Amet, Tohti, Shikuma, Cecilia, Shiramizu, Bruce, Halperin, Jose A., Qin, Xuebin
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272871/
https://ncbi.nlm.nih.gov/pubmed/19955519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902278
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