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Generation and phenotyping of mCd59a and mCd59b double-knockout mice

CD59 is a membrane protein inhibitor of the membrane attack complex (MAC) of complement. Humans express only one, whereas mice express two CD59 genes. We previously reported the targeted deletion of the mCd59b gene in which absence of mCd59b together with an unintended down regulation of mCd59a caus...

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Détails bibliographiques
Publié dans:Am J Hematol
Auteurs principaux: Qin, Xuebin, Hu, Weiguo, Song, Wenping, Grubissich, Luciano, Hu, Xuemei, Wu, Gongxiong, Ferris, Sean, Dobarro, Martin, Halperin, Jose A.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280255/
https://ncbi.nlm.nih.gov/pubmed/19051264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21319
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