Complement regulator CD59 protects against atherosclerosis by restricting the formation of complement membrane attack complex

Complement is a central effector system within the immune system and is implicated in a range of inflammatory disorders. CD59 is a key regulator of complement membrane attack complex (MAC) assembly. The atherogenic role of terminal complement has long been suspected, but is still unclear. Here, we d...

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Veröffentlicht in:Circ Res
Hauptverfasser: Wu, Gongxiong, Hu, Weiguo, Shahsafaei, Aliakbar, Song, Wenping, Dobarro, Martin, Sukhova, Galina K, Bronson, Rod R., Shi, Guo-ping, Rother, Russell P., Halperin, Jose A., Qin, Xuebin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267695/
https://ncbi.nlm.nih.gov/pubmed/19131645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.191361
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