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Glycation of the Complement Regulatory Protein CD59 Is a Novel Biomarker for Glucose Handling in Humans

CONTEXT: Human CD59, an inhibitor of the membrane attack complex of complement, is inactivated by glycation. Glycation inactivation of CD59 enhances complement-mediated injury in target organs of diabetes complications. OBJECTIVE: We hypothesized that circulating soluble glycated CD59 (GCD59) repres...

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Bibliografski detalji
Glavni autori: Ghosh, Pamela, Vaidya, Anand, Sahoo, Rupam, Goldfine, Allison, Herring, Neil, Bry, Lynn, Chorev, Michael, Halperin, Jose A.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037733/
https://ncbi.nlm.nih.gov/pubmed/24628556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-4232
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