The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model

Pulmonary arterial hypertension (PAH) is suspected to be a strong mortality determinant of hemolytic disorders. However, direct contribution of acute intravascular hemolysis to fatal PAH has not been investigated. The roles of nitric oxide (NO) insufficiency and platelet activation in hemolysis-asso...

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Detalhes bibliográficos
Main Authors: Hu, Weiguo, Jin, Richard, Zhang, Jinyan, You, Tao, Peng, Zhihai, Ge, Xiaowen, Bronson, Roderick T., Halperin, Jose A., Loscalzo, Joseph, Qin, Xuebin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938847/
https://ncbi.nlm.nih.gov/pubmed/20511540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-267112
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