Impact of CD1d Deficiency on Metabolism

Por Kotas, Maya E., Lee, Hui-Young, Gillum, Matthew P., Annicelli, Charles, Guigni, Blas A., Shulman, Gerald I., Medzhitov, Ruslan
Publicado em 2011

Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

Por Jornayvaz, François R., Birkenfeld, Andreas L., Jurczak, Michael J., Kanda, Shoichi, Guigni, Blas A., Jiang, Debbie C., Zhang, Dongyan, Lee, Hui-Young, Samuel, Varman T., Shulman, Gerald I.
Publicado em 2011

Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-ou...

Por Jurczak, Michael J., Lee, Ann-Hwee, Jornayvaz, Francois R., Lee, Hui-Young, Birkenfeld, Andreas L., Guigni, Blas A., Kahn, Mario, Samuel, Varman T., Glimcher, Laurie H., Shulman, Gerald I.
Publicado em 2012

Thyroid Hormone Receptor-α Gene Knockout Mice Are Protected from Diet-Induced Hepatic Insulin Resistance

Por Jornayvaz, François R., Lee, Hui-Young, Jurczak, Michael J., Alves, Tiago C., Guebre-Egziabher, Fitsum, Guigni, Blas A., Zhang, Dongyan, Samuel, Varman T., Silva, J. Enrique, Shulman, Gerald I.
Publicado em 2012

Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice

Por Camporez, João Paulo G., Jornayvaz, François R., Petersen, Max C., Pesta, Dominik, Guigni, Blas A., Serr, Julie, Zhang, Dongyan, Kahn, Mario, Samuel, Varman T., Jurczak, Michael J., Shulman, Gerald I.
Publicado em 2013

Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo

Por Galbo, Thomas, Perry, Rachel J., Jurczak, Michael J., Camporez‎, João-Paulo G., Alves, Tiago C., Kahn, Mario, Guigni, Blas A., Serr, Julie, Zhang, Dongyan, Bhanot, Sanjay, Samuel, Varman T., Shulman, Gerald I.
Publicado em 2013

Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance

Por Camporez, João Paulo G., Jornayvaz, François R., Lee, Hui-Young, Kanda, Shoichi, Guigni, Blas A., Kahn, Mario, Samuel, Varman T., Carvalho, Carla R.O., Petersen, Kitt Falk, Jurczak, Michael J., Shulman, Gerald I.
Publicado em 2013

Second-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance

Por Popov, Violeta B., Jornayvaz, Francois R., Akgul, Emin O., Kanda, Shoichi, Jurczak, Michael J., Zhang, Dongyan, Abudukadier, Abulizi, Majumdar, Sachin K., Guigni, Blas, Petersen, Kitt Falk, Manchem, Vara Prasad, Bhanot, Sanjay, Shulman, Gerald I., Samuel, Varman T.
Publicado no FASEB J (2016)

Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism

Por Brown, Whitney H., Gillum, Matthew P., Lee, Hui-Young, Camporez, Joao Paulo G., Zhang, Xian-man, Jeong, Jin Kwon, Alves, Tiago C., Erion, Derek M., Guigni, Blas A., Kahn, Mario, Samuel, Varman T., Cravatt, Benjamin F., Diano, Sabrina, Shulman, Gerald I.
Publicado em 2012

Apolipoprotein CIII Overexpressing Mice Are Predisposed to Diet-Induced Hepatic Steatosis and Hepatic Insulin Resistance

Por Lee, Hui-Young, Birkenfeld, Andreas L, Jornayvaz, Francois R, Jurczak, Michael J, Kanda, Shoichi, Popov, Violeta, Frederick, David W, Zhang, Dongyan, Guigni, Blas, Bharadwaj, Kalyani G, Choi, Cheol Soo, Goldberg, Ira J, Park, Jae-Hak, Petersen, Kitt F, Samuel, Varman T, Shulman, Gerald I
Publicado em 2011

Muscle-specific activation of Ca(2+)/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice

Por Lee, Hui-Young, Gattu, Arijeet K., Camporez, João-Paulo G., Kanda, Shoichi, Guigni, Blas, Kahn, Mario, Zhang, Dongyan, Galbo, Thomas, Birkenfeld, Andreas L., Jornayvaz, Francois R., Jurczak, Michael J., Choi, Cheol Soo, Yan, Zhen, Williams, R. Sanders, Shulman, Gerald I., Samuel, Varman T.
Publicado no Diabetologia (2014)

Influence of the Hepatic Eukaryotic Initiation Factor 2α (eIF2α) Endoplasmic Reticulum (ER) Stress Response Pathway on Insulin-mediated ER Stress and Hepatic and Peripheral Glucose...

Por Birkenfeld, Andreas L., Lee, Hui-Young, Majumdar, Sachin, Jurczak, Michael J., Camporez, Joao Paulo, Jornayvaz, Francois R., Frederick, David W., Guigni, Blas, Kahn, Mario, Zhang, Dongyang, Weismann, Dirk, Arafat, Ayman M., Pfeiffer, Andreas F., Lieske, Stefanie, Oyadomari, Seiichi, Ron, David, Samuel, Varman T., Shulman, Gerald I.
Publicado em 2011

CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance

Por Cantley, Jennifer L., Yoshimura, Toru, Camporez, Joao Paulo G., Zhang, Dongyan, Jornayvaz, Francois R., Kumashiro, Naoki, Guebre-Egziabher, Fitsum, Jurczak, Michael J., Kahn, Mario, Guigni, Blas A., Serr, Julie, Hankin, Joseph, Murphy, Robert C., Cline, Gary W., Bhanot, Sanjay, Manchem, Vara Prasad, Brown, J. Mark, Samuel, Varman T., Shulman, Gerald I.
Publicado em 2013

Targeting Pyruvate Carboxylase Reduces Gluconeogenesis and Adiposity and Improves Insulin Resistance

Por Kumashiro, Naoki, Beddow, Sara A., Vatner, Daniel F., Majumdar, Sachin K., Cantley, Jennifer L., Guebre-Egziabher, Fitsum, Fat, Ioana, Guigni, Blas, Jurczak, Michael J., Birkenfeld, Andreas L., Kahn, Mario, Perler, Bryce K., Puchowicz, Michelle A., Manchem, Vara Prasad, Bhanot, Sanjay, Still, Christopher D., Gerhard, Glenn S., Petersen, Kitt Falk, Cline, Gary W., Shulman, Gerald I., Samuel, Varman T.
Publicado em 2013