Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice

Hepatic insulin resistance has been attributed to both increased endoplasmic reticulum (ER) stress and accumulation of intracellular lipids, specifically diacylglycerol (DAG). The ER stress response protein, X-box-binding protein-1 (XBP1), was recently shown to regulate hepatic lipogenesis, suggesti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jurczak, Michael J., Lee, Ann-Hwee, Jornayvaz, Francois R., Lee, Hui-Young, Birkenfeld, Andreas L., Guigni, Blas A., Kahn, Mario, Samuel, Varman T., Glimcher, Laurie H., Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268415/
https://ncbi.nlm.nih.gov/pubmed/22128176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.316760
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados