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Molecular Pathways: Immunosuppressive Roles of IRE1α–XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment

The endoplasmic reticulum (ER) is a massive cytoplasmic membrane network that functions primarily to ensure proper folding and post-translational modification of newly synthesized secretory and transmembrane proteins. Abnormal accumulation of unfolded proteins in this organelle causes a state of “ER...

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Bibliografski detalji
Izdano u:Clin Cancer Res
Glavni autori: Cubillos-Ruiz, Juan R., Bettigole, Sarah E., Glimcher, Laurie H.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854763/
https://ncbi.nlm.nih.gov/pubmed/26979393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1570
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