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Molecular Pathways: Immunosuppressive Roles of IRE1α–XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment
The endoplasmic reticulum (ER) is a massive cytoplasmic membrane network that functions primarily to ensure proper folding and post-translational modification of newly synthesized secretory and transmembrane proteins. Abnormal accumulation of unfolded proteins in this organelle causes a state of “ER...
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| Publicado no: | Clin Cancer Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854763/ https://ncbi.nlm.nih.gov/pubmed/26979393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1570 |
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