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Regulation of hepatic lipogenesis by the transcription factor XBP1

Dietary carbohydrates regulate hepatic lipogenesis by controlling the expression of critical enzymes in glycolytic and lipogenic pathways. Here we report that the transcription factor XBP1, a key regulator of the Unfolded Protein Response (UPR), is required for the unrelated function of normal fatty...

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Detalhes bibliográficos
Main Authors: Lee, Ann-Hwee, Scapa, Erez F., Cohen, David E., Glimcher, Laurie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620093/
https://ncbi.nlm.nih.gov/pubmed/18556558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1158042
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