Llwytho...
Toll-like receptor activation of XBP1 regulates innate immune responses in macrophages
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate adaptive responses to specific insults. Here we report that TLR4 and TLR2 specifically activated the endoplasmic reticulum (ER)-stress sensor kinase IRE1α and its downstrea...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2010
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113706/ https://ncbi.nlm.nih.gov/pubmed/20351694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1857 |
| Tagiau: |
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