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Regulation of Innate Immunity by signaling pathways emerging from the endoplasmic reticulum

The innate immune system has evolved the capacity to detect specific pathogens and to interrogate cell and tissue integrity in order to mount an appropriate immune response. Loss of homeostasis in the endoplasmic reticulum (ER) triggers the ER-stress response, a hallmark of many inflammatory and inf...

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Detalhes bibliográficos
Main Authors: Martinon, Fabio, Glimcher, Laurie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042531/
https://ncbi.nlm.nih.gov/pubmed/21094031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.10.016
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