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Toll-like receptor activation of XBP1 regulates innate immune responses in macrophages
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate adaptive responses to specific insults. Here we report that TLR4 and TLR2 specifically activated the endoplasmic reticulum (ER)-stress sensor kinase IRE1α and its downstrea...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113706/ https://ncbi.nlm.nih.gov/pubmed/20351694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1857 |
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