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Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis
The unfolded protein response (UPR) is a conserved adaptive reaction that increases cell survival under endoplasmic reticulum (ER) stress conditions. X-box-binding protein-1 (XBP-1) is a key transcriptional regulator of the UPR that activates genes involved in protein folding, secretion, and degrada...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206609/ https://ncbi.nlm.nih.gov/pubmed/18178615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711094105 |
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