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Perturbation of Endoplasmic Reticulum Homeostasis Facilitates Prion Replication
Prion diseases are fatal and infectious neurodegenerative disorders characterized by the accumulation of an abnormally folded form of the prion protein (PrP), termed PrP(Sc). Prion replication triggers endoplasmic reticulum (ER) stress, neuronal dysfunction, and apoptosis. In this study we analyze t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804266/ https://ncbi.nlm.nih.gov/pubmed/17329244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611909200 |
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