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Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis

The unfolded protein response (UPR) is a conserved adaptive reaction that increases cell survival under endoplasmic reticulum (ER) stress conditions. X-box-binding protein-1 (XBP-1) is a key transcriptional regulator of the UPR that activates genes involved in protein folding, secretion, and degrada...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hetz, Claudio, Lee, Ann-Hwee, Gonzalez-Romero, Dennisse, Thielen, Peter, Castilla, Joaquín, Soto, Claudio, Glimcher, Laurie H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206609/
https://ncbi.nlm.nih.gov/pubmed/18178615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711094105
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