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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

The mammalian unfolded protein response (UPR) protects the cell against the stress of misfolded proteins in the endoplasmic reticulum (ER). We have investigated here the contribution of the UPR transcription factors XBP-1, ATF6α, and ATF6β to UPR target gene expression. Gene profiling of cell lines...

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Detalhes bibliográficos
Main Authors: Lee, Ann-Hwee, Iwakoshi, Neal N., Glimcher, Laurie H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC207643/
https://ncbi.nlm.nih.gov/pubmed/14559994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7448-7459.2003
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