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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

The mammalian unfolded protein response (UPR) protects the cell against the stress of misfolded proteins in the endoplasmic reticulum (ER). We have investigated here the contribution of the UPR transcription factors XBP-1, ATF6α, and ATF6β to UPR target gene expression. Gene profiling of cell lines...

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Main Authors: Lee, Ann-Hwee, Iwakoshi, Neal N., Glimcher, Laurie H.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC207643/
https://ncbi.nlm.nih.gov/pubmed/14559994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7448-7459.2003
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