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XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

The secretory function of cells relies on the capacity of the endoplasmic reticulum (ER) to fold and modify nascent polypeptides and to synthesize phospholipids for the subsequent trafficking of secretory proteins through the ER–Golgi network. We have previously demonstrated that the transcription f...

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Detalhes bibliográficos
Main Authors: Lee, Ann-Hwee, Chu, Gerald C, Iwakoshi, Neal N, Glimcher, Laurie H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356340/
https://ncbi.nlm.nih.gov/pubmed/16362047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600903
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