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XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

The secretory function of cells relies on the capacity of the endoplasmic reticulum (ER) to fold and modify nascent polypeptides and to synthesize phospholipids for the subsequent trafficking of secretory proteins through the ER–Golgi network. We have previously demonstrated that the transcription f...

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Détails bibliographiques
Auteurs principaux: Lee, Ann-Hwee, Chu, Gerald C, Iwakoshi, Neal N, Glimcher, Laurie H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356340/
https://ncbi.nlm.nih.gov/pubmed/16362047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600903
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