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XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

The secretory function of cells relies on the capacity of the endoplasmic reticulum (ER) to fold and modify nascent polypeptides and to synthesize phospholipids for the subsequent trafficking of secretory proteins through the ER–Golgi network. We have previously demonstrated that the transcription f...

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Bibliographic Details
Main Authors: Lee, Ann-Hwee, Chu, Gerald C, Iwakoshi, Neal N, Glimcher, Laurie H
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356340/
https://ncbi.nlm.nih.gov/pubmed/16362047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600903
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