Loading...

XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells

Differentiation of B cells into plasma cells requires X-box binding protein–1 (XBP-1). In the absence of XBP-1, B cells develop normally, but very little immunoglobulin is secreted. XBP-1 controls the expression of a large set of genes whose products participate in expansion of the endoplasmic retic...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Tirosh, Boaz, Iwakoshi, Neal N., Glimcher, Laurie H., Ploegh, Hidde L.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212843/
https://ncbi.nlm.nih.gov/pubmed/16103408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050575
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!