Loading...
XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells
Differentiation of B cells into plasma cells requires X-box binding protein–1 (XBP-1). In the absence of XBP-1, B cells develop normally, but very little immunoglobulin is secreted. XBP-1 controls the expression of a large set of genes whose products participate in expansion of the endoplasmic retic...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2005
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212843/ https://ncbi.nlm.nih.gov/pubmed/16103408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050575 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|