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Polymer IgM assembly and secretion in lymphoid and nonlymphoid cell lines: evidence that J chain is required for pentamer IgM synthesis.

The requirements for IgM assembly and secretion were evaluated by introducing a constitutively expressed J-chain cDNA into lymphoid and nonlymphoid cell lines expressing the secretory form of monomer IgM. Assays of cell lysates and supernatants showed that only secretory monomer IgM is required for...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Niles, M J, Matsuuchi, L, Koshland, M E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42323/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708742/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2884
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