Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

le Swamy, Mahima, Pathak, Shalini, Grzes, Katarzyna M., Damerow, Sebastian, Sinclair, Linda V., van Aalten, Daan M. F., Cantrell, Doreen A.
Foilsithe in Nat Immunol (2016)

The cytotoxic T cell proteome and its shaping by mammalian Target of Rapamycin

le Hukelmann, Jens L., Anderson, Karen E., Sinclair, Linda V., Grzes, Katarzyna M., Murillo, Alejandro Brenes, Hawkins, Phillip T., Stephens, Len R., Lamond, Angus I., Cantrell, Doreen A.
Foilsithe in Nat Immunol (2015)

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

le Vara-Ciruelos, Diana, Dandapani, Madhumita, Russell, Fiona M., Grzes, Katarzyna M., Atrih, Abdelmadjid, Foretz, Marc, Viollet, Benoit, Lamont, Douglas J., Cantrell, Doreen A., Hardie, D. Grahame
Foilsithe in Cell Rep (2019)

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

le Frost, Julianty, Galdeano, Carles, Soares, Pedro, Gadd, Morgan S., Grzes, Katarzyna M., Ellis, Lucy, Epemolu, Ola, Shimamura, Satoko, Bantscheff, Marcus, Grandi, Paola, Read, Kevin D., Cantrell, Doreen A., Rocha, Sonia, Ciulli, Alessio
Foilsithe in Nat Commun (2016)

Loss of beta2-integrin-mediated cytoskeletal linkage reprograms dendritic cells to a mature migratory phenotype

le Morrison, Vicky Louise, James, Martyn John, Grzes, Katarzyna, Cook, Peter, Glass, David Gavin, Savinko, Terhi, Lek, Hwee San, Gawden-Bone, Christian, Watts, Colin, Millington, Owain Richard, MacDonald, Andrew Scott, Fagerholm, Susanna Carola
Foilsithe in Nat Commun (2014)

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

le Field, Cameron S., Baixauli, Francesc, Kyle, Ryan L., Puleston, Daniel J., Cameron, Alanna M., Sanin, David E., Hippen, Keli L., Loschi, Michael, Thangavelu, Govindarajan, Corrado, Mauro, Edwards-Hicks, Joy, Grzes, Katarzyna M., Pearce, Edward J., Blazar, Bruce R., Pearce, Erika L.
Foilsithe in Cell Metab (2020)

Dynamic Cardiolipin Synthesis Is Required for CD8(+) T Cell Immunity

le Corrado, Mauro, Edwards-Hicks, Joy, Villa, Matteo, Flachsmann, Lea J., Sanin, David E., Jacobs, Maaike, Baixauli, Francesc, Stanczak, Michal, Anderson, Eve, Azuma, Mai, Quintana, Andrea, Curtis, Jonathan D., Clapes, Thomas, Grzes, Katarzyna M., Kabat, Agnieszka M., Kyle, Ryan, Patterson, Annette E., Geltink, Ramon Klein, Amulic, Borko, Steward, Colin G., Strathdee, Douglas, Trompouki, Eirini, O’Sullivan, David, Pearce, Edward J., Pearce, Erika L.
Foilsithe in Cell Metab (2020)

Acetate Promotes T Cell Effector Function during Glucose Restriction

le Qiu, Jing, Villa, Matteo, Sanin, David E., Buck, Michael D., O’Sullivan, David, Ching, Reagan, Matsushita, Mai, Grzes, Katarzyna M., Winkler, Frances, Chang, Chih-Hao, Curtis, Jonathan D., Kyle, Ryan L., Van Teijlingen Bakker, Nikki, Corrado, Mauro, Haessler, Fabian, Alfei, Francesca, Edwards-Hicks, Joy, Maggi, Leonard B., Zehn, Dietmar, Egawa, Takeshi, Bengsch, Bertram, Klein Geltink, Ramon I., Jenuwein, Thomas, Pearce, Edward J., Pearce, Erika L.
Foilsithe in Cell Rep (2019)

Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2

le Sanin, David E., Matsushita, Mai, Geltink, Ramon I. Klein, Grzes, Katarzyna M., van Teijlingen Bakker, Nikki, Corrado, Mauro, Kabat, Agnieszka M., Buck, Michael D., Qiu, Jing, Lawless, Simon J., Cameron, Alanna M., Villa, Matteo, Baixauli, Francesc, Patterson, Annette E., Hässler, Fabian, Curtis, Jonathan D., O’Neill, Christina M., O’Sullivan, David, Wu, Duojiao, Mittler, Gerhard, Huang, Stanley Ching-Cheng, Pearce, Erika L., Pearce, Edward J.
Foilsithe in Immunity (2018)

Fever supports CD8(+) effector T cell responses by promoting mitochondrial translation

le O’Sullivan, David, Stanczak, Michal A., Villa, Matteo, Uhl, Franziska M., Corrado, Mauro, Klein Geltink, Ramon I., Sanin, David E., Apostolova, Petya, Rana, Nisha, Edwards-Hicks, Joy, Grzes, Katarzyna M., Kabat, Agnieszka M., Kyle, Ryan L., Fabri, Mario, Curtis, Jonathan D., Buck, Michael D., Patterson, Annette E., Regina, Annamaria, Field, Cameron S., Baixauli, Francesc, Puleston, Daniel J., Pearce, Edward J., Zeiser, Robert, Pearce, Erika L.
Foilsithe in Proc Natl Acad Sci U S A (2021)

Mitochondrial Priming By CD28

le Klein Geltink, Ramon I., O’Sullivan, David, Corrado, Mauro, Bremser, Anna, Buck, Michael D., Buescher, Joerg M., Firat, Elke, Zhu, Xuekai, Niedermann, Gabriele, Caputa, George, Kelly, Beth, Warthorst, Ursula, Rensing-Ehl, Anne, Kyle, Ryan L., Vandersarren, Lana, Curtis, Jonathan D., Patterson, Annette E., Lawless, Simon, Grzes, Katarzyna, Qiu, Jing, Sanin, David E., Kretz, Oliver, Huber, Tobias B., Janssens, Sophie, Lambrecht, Bart N., Rambold, Angelika S., Pearce, Edward J., Pearce, Erika L.
Foilsithe in Cell (2017)

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

le Puleston, Daniel J., Buck, Michael D., Klein Geltink, Ramon I., Kyle, Ryan L., Caputa, George, O’Sullivan, David, Cameron, Alanna M., Castoldi, Angela, Musa, Yaarub, Kabat, Agnieszka M., Zhang, Ying, Flachsmann, Lea J., Field, Cameron S., Patterson, Annette E., Scherer, Stefanie, Alfei, Francesca, Baixauli, Francesc, Austin, S. Kyle, Kelly, Beth, Matsushita, Mai, Curtis, Jonathan D., Grzes, Katarzyna M., Villa, Matteo, Corrado, Mauro, Sanin, David E., Qiu, Jing, Pällman, Nora, Paz, Katelyn, Maccari, Maria Elena, Blazar, Bruce R., Mittler, Gerhard, Buescher, Joerg M., Zehn, Dietmar, Rospert, Sabine, Pearce, Edward J., Balabanov, Stefan, Pearce, Erika L.
Foilsithe in Cell Metab (2019)