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Dynamic Cardiolipin Synthesis Is Required for CD8(+) T Cell Immunity
Mitochondria constantly adapt to the metabolic needs of a cell. This mitochondrial plasticity is critical to T cells, which modulate metabolism depending on antigen-driven signals and environment. We show here that de novo synthesis of the mitochondrial membrane-specific lipid cardiolipin maintains...
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| Publicado en: | Cell Metab |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cell Press
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7721104/ https://ncbi.nlm.nih.gov/pubmed/33264603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.11.003 |
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