Mitochondrial Priming By CD28

T cell receptor (TCR) signaling without CD28 can elicit primary effector T cells, but memory T cells generated during this process are anergic, failing to respond to secondary antigen exposure. We show that upon T cell activation, CD28 transiently promotes expression of carnitine palmitoyltransferas...

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發表在:Cell
Main Authors: Klein Geltink, Ramon I., O’Sullivan, David, Corrado, Mauro, Bremser, Anna, Buck, Michael D., Buescher, Joerg M., Firat, Elke, Zhu, Xuekai, Niedermann, Gabriele, Caputa, George, Kelly, Beth, Warthorst, Ursula, Rensing-Ehl, Anne, Kyle, Ryan L., Vandersarren, Lana, Curtis, Jonathan D., Patterson, Annette E., Lawless, Simon, Grzes, Katarzyna, Qiu, Jing, Sanin, David E., Kretz, Oliver, Huber, Tobias B., Janssens, Sophie, Lambrecht, Bart N., Rambold, Angelika S., Pearce, Edward J., Pearce, Erika L.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637396/
https://ncbi.nlm.nih.gov/pubmed/28919076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.018
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