Mitochondrial Priming By CD28

T cell receptor (TCR) signaling without CD28 can elicit primary effector T cells, but memory T cells generated during this process are anergic, failing to respond to secondary antigen exposure. We show that upon T cell activation, CD28 transiently promotes expression of carnitine palmitoyltransferas...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Klein Geltink, Ramon I., O’Sullivan, David, Corrado, Mauro, Bremser, Anna, Buck, Michael D., Buescher, Joerg M., Firat, Elke, Zhu, Xuekai, Niedermann, Gabriele, Caputa, George, Kelly, Beth, Warthorst, Ursula, Rensing-Ehl, Anne, Kyle, Ryan L., Vandersarren, Lana, Curtis, Jonathan D., Patterson, Annette E., Lawless, Simon, Grzes, Katarzyna, Qiu, Jing, Sanin, David E., Kretz, Oliver, Huber, Tobias B., Janssens, Sophie, Lambrecht, Bart N., Rambold, Angelika S., Pearce, Edward J., Pearce, Erika L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637396/
https://ncbi.nlm.nih.gov/pubmed/28919076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.018
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