Mitochondrial Priming By CD28

T cell receptor (TCR) signaling without CD28 can elicit primary effector T cells, but memory T cells generated during this process are anergic, failing to respond to secondary antigen exposure. We show that upon T cell activation, CD28 transiently promotes expression of carnitine palmitoyltransferas...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Klein Geltink, Ramon I., O’Sullivan, David, Corrado, Mauro, Bremser, Anna, Buck, Michael D., Buescher, Joerg M., Firat, Elke, Zhu, Xuekai, Niedermann, Gabriele, Caputa, George, Kelly, Beth, Warthorst, Ursula, Rensing-Ehl, Anne, Kyle, Ryan L., Vandersarren, Lana, Curtis, Jonathan D., Patterson, Annette E., Lawless, Simon, Grzes, Katarzyna, Qiu, Jing, Sanin, David E., Kretz, Oliver, Huber, Tobias B., Janssens, Sophie, Lambrecht, Bart N., Rambold, Angelika S., Pearce, Edward J., Pearce, Erika L.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637396/
https://ncbi.nlm.nih.gov/pubmed/28919076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.018
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