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Acetate Promotes T Cell Effector Function during Glucose Restriction
Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic adaptation to the surrounding microenvironment is therefore key for maintaining appropriate cell function. For instance, cancer cells use acetate as a substra...
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| Publicado en: | Cell Rep |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544383/ https://ncbi.nlm.nih.gov/pubmed/31091446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.022 |
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