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Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation
How cells adapt metabolism to meet demands is an active area of interest across biology. Among a broad range of functions, the polyamine spermidine is needed to hypusinate the translation factor eukaryotic initiation factor 5A (eIF5A). We show here that hypusinated eIF5A (eIF5A(H)) promotes the effi...
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| Veröffentlicht in: | Cell Metab |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688828/ https://ncbi.nlm.nih.gov/pubmed/31130465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.05.003 |
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