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Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification

A naturally occurring unusual amino acid, hypusine [N(ε)-(4-amino-2-hydroxybutyl)-lysine] is a component of a single cellular protein, eukaryotic translation initiation factor 5A (eIF5A). It is a modified lysine with structural contribution from the polyamine spermidine. Hypusine is formed in a nove...

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Autori principali: Wolff, E. C., Kang, K. R., Kim, Y. S., Park, M. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572820/
https://ncbi.nlm.nih.gov/pubmed/17476569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-007-0525-0
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