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Functional significance of eIF5A and its hypusine modification in eukaryotes

The unusual basic amino acid, hypusine [N(ε)-(4-amino-2-hydroxybutyl)-lysine], is a modified lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. This naturally occurring amino acid is a product of a unique posttranslational modification that occurs in only one cellular...

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Main Authors: Park, M. H., Nishimura, K., Zanelli, C. F., Valentini, S. R.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829442/
https://ncbi.nlm.nih.gov/pubmed/19997760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-009-0408-7
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