Crystal structure and mechanism of CO dehydrogenase, a molybdo iron-sulfur flavoprotein containing S-selanylcysteine

por Dobbek, Holger, Gremer, Lothar, Meyer, Ortwin, Huber, Robert
Publicado 1999

Catalysis at a dinuclear [CuSMo([Image: see text] O)OH] cluster in a CO dehydrogenase resolved at 1.1-Å resolution

por Dobbek, Holger, Gremer, Lothar, Kiefersauer, Reiner, Huber, Robert, Meyer, Ortwin
Publicado 2002

Purification and Characterization of Recombinant N-Terminally Pyroglutamate-Modified Amyloid-β Variants and Structural Analysis by Solution NMR Spectroscopy

por Dammers, Christina, Gremer, Lothar, Neudecker, Philipp, Demuth, Hans-Ulrich, Schwarten, Melanie, Willbold, Dieter
Publicado en PLoS One (2015)

Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment Is Part of the β-Sheet Core

por Weirich, Franziska, Gremer, Lothar, Mirecka, Ewa A., Schiefer, Stephanie, Hoyer, Wolfgang, Heise, Henrike
Publicado en PLoS One (2016)

Clustering of human prion protein and α-synuclein oligomers requires the prion protein N-terminus

por Rösener, Nadine S., Gremer, Lothar, Wördehoff, Michael M., Kupreichyk, Tatsiana, Etzkorn, Manuel, Neudecker, Philipp, Hoyer, Wolfgang
Publicado en Commun Biol (2020)

β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor

por Mirecka, Ewa A., Feuerstein, Sophie, Gremer, Lothar, Schröder, Gunnar F., Stoldt, Matthias, Willbold, Dieter, Hoyer, Wolfgang
Publicado en Sci Rep (2016)

Pyroglutamate-Modified Amyloid-β(3–42) Shows α-Helical Intermediates before Amyloid Formation

por Dammers, Christina, Reiss, Kerstin, Gremer, Lothar, Lecher, Justin, Ziehm, Tamar, Stoldt, Matthias, Schwarten, Melanie, Willbold, Dieter
Publicado en Biophys J (2017)

A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography

por Rusitzka, Kristiane A. K., Stephenson, Leigh T., Szczepaniak, Agnieszka, Gremer, Lothar, Raabe, Dierk, Willbold, Dieter, Gault, Baptiste
Publicado en Sci Rep (2018)

Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling (RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (...

por Jaiswal, Mamta, Gremer, Lothar, Dvorsky, Radovan, Haeusler, Lars Christian, Cirstea, Ion C., Uhlenbrock, Katharina, Ahmadian, Mohammad Reza
Publicado 2011

Analysis of the Bin1 SH3 interaction with peptides derived from the hepatitis C virus protein NS5A and c-Myc reveals that NS5A can competitively displace c-Myc in vitro

por Aladağ, Amine, Bösing, Christina, Gremer, Lothar, Hoffmann, Silke, Klinker, Stefan, Schwarten, Melanie, Stoldt, Matthias, Valdau, Olga, Willbold, Dieter
Publicado 2014

Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth

por Wördehoff, Michael M., Shaykhalishahi, Hamed, Groß, Luca, Gremer, Lothar, Stoldt, Matthias, Buell, Alexander K., Willbold, Dieter, Hoyer, Wolfgang
Publicado en J Mol Biol (2017)

A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion protein

por Rösener, Nadine S., Gremer, Lothar, Reinartz, Elke, König, Anna, Brener, Oleksandr, Heise, Henrike, Hoyer, Wolfgang, Neudecker, Philipp, Willbold, Dieter
Publicado en J Biol Chem (2018)

The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction

por Pena, Vladimir, Hothorn, Michael, Eberth, Alexander, Kaschau, Nikolai, Parret, Annabel, Gremer, Lothar, Bonneau, Fabien, Ahmadian, Mohammad Reza, Scheffzek, Klaus
Publicado 2008

Germline KRAS Mutations Cause Aberrant Biochemical and Physical Properties Leading to Developmental Disorders

por Gremer, Lothar, Merbitz-Zahradnik, Torsten, Dvorsky, Radovan, Cirstea, Ion C., Kratz, Christian Peter, Zenker, Martin, Wittinghofer, Alfred, Ahmadian, Mohammad Reza
Publicado 2010

Structural details of amyloid β oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopy

por König, Anna S., Rösener, Nadine S., Gremer, Lothar, Tusche, Markus, Flender, Daniel, Reinartz, Elke, Hoyer, Wolfgang, Neudecker, Philipp, Willbold, Dieter, Heise, Henrike
Publicado en J Biol Chem (2021)

Liposome Reconstitution and Modulation of Recombinant Prenylated Human Rac1 by GEFs, GDI1 and Pak1

por Zhang, Si-Cai, Gremer, Lothar, Heise, Henrike, Janning, Petra, Shymanets, Aliaksei, Cirstea, Ion C., Krause, Eberhard, Nürnberg, Bernd, Ahmadian, Mohammad Reza
Publicado 2014

IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

por Nouri, Kazem, Fansa, Eyad K., Amin, Ehsan, Dvorsky, Radovan, Gremer, Lothar, Willbold, Dieter, Schmitt, Lutz, Timson, David J., Ahmadian, Mohammad R.
Publicado en J Biol Chem (2016)

Structural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol

por Dammers, Christina, Gremer, Lothar, Reiß, Kerstin, Klein, Antonia N., Neudecker, Philipp, Hartmann, Rudolf, Sun, Na, Demuth, Hans-Ulrich, Schwarten, Melanie, Willbold, Dieter
Publicado en PLoS One (2015)

Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication

por Klinker, Stefan, Stindt, Sabine, Gremer, Lothar, Bode, Johannes G., Gertzen, Christoph G. W., Gohlke, Holger, Weiergräber, Oliver H., Hoffmann, Silke, Willbold, Dieter
Publicado en J Biol Chem (2019)

Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

por Röder, Christine, Vettore, Nicola, Mangels, Lena N., Gremer, Lothar, Ravelli, Raimond B. G., Willbold, Dieter, Hoyer, Wolfgang, Buell, Alexander K., Schröder, Gunnar F.
Publicado en Nat Commun (2019)