IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

IQ motif-containing GTPase activating protein 1 (IQGAP1) plays a central role in the physical assembly of relevant signaling networks that are responsible for various cellular processes, including cell adhesion, polarity, and transmigration. The RHO family proteins CDC42 and RAC1 have been shown to...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nouri, Kazem, Fansa, Eyad K., Amin, Ehsan, Dvorsky, Radovan, Gremer, Lothar, Willbold, Dieter, Schmitt, Lutz, Timson, David J., Ahmadian, Mohammad R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159498/
https://ncbi.nlm.nih.gov/pubmed/27815503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752121
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