IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

IQ motif-containing GTPase activating protein 1 (IQGAP1) plays a central role in the physical assembly of relevant signaling networks that are responsible for various cellular processes, including cell adhesion, polarity, and transmigration. The RHO family proteins CDC42 and RAC1 have been shown to...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Nouri, Kazem, Fansa, Eyad K., Amin, Ehsan, Dvorsky, Radovan, Gremer, Lothar, Willbold, Dieter, Schmitt, Lutz, Timson, David J., Ahmadian, Mohammad R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159498/
https://ncbi.nlm.nih.gov/pubmed/27815503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752121
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