IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

IQ motif-containing GTPase activating protein 1 (IQGAP1) plays a central role in the physical assembly of relevant signaling networks that are responsible for various cellular processes, including cell adhesion, polarity, and transmigration. The RHO family proteins CDC42 and RAC1 have been shown to...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Nouri, Kazem, Fansa, Eyad K., Amin, Ehsan, Dvorsky, Radovan, Gremer, Lothar, Willbold, Dieter, Schmitt, Lutz, Timson, David J., Ahmadian, Mohammad R.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159498/
https://ncbi.nlm.nih.gov/pubmed/27815503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752121
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