IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

IQ motif-containing GTPase activating protein 1 (IQGAP1) plays a central role in the physical assembly of relevant signaling networks that are responsible for various cellular processes, including cell adhesion, polarity, and transmigration. The RHO family proteins CDC42 and RAC1 have been shown to...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Nouri, Kazem, Fansa, Eyad K., Amin, Ehsan, Dvorsky, Radovan, Gremer, Lothar, Willbold, Dieter, Schmitt, Lutz, Timson, David J., Ahmadian, Mohammad R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159498/
https://ncbi.nlm.nih.gov/pubmed/27815503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752121
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