Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS

RHO GTPase-activating proteins (RHOGAPs) are one of the major classes of regulators of the RHO-related protein family that are crucial in many cellular processes, motility, contractility, growth, differentiation, and development. Using database searches, we extracted 66 distinct human RHOGAPs, from...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Amin, Ehsan, Jaiswal, Mamta, Derewenda, Urszula, Reis, Katarina, Nouri, Kazem, Koessmeier, Katja T., Aspenström, Pontus, Somlyo, Avril V., Dvorsky, Radovan, Ahmadian, Mohammad R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034035/
https://ncbi.nlm.nih.gov/pubmed/27481945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.736967
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