From Genetics of Inflammatory Bowel Disease Towards Mechanistic Insights

Por Graham, Daniel B., Xavier, Ramnik J.
Publicado em 2013

Resources for the design of CRISPR gene editing experiments

Por Graham, Daniel B., Root, David E.
Publicado no Genome Biol (2015)

Vav/Phospholipase Cγ2–Mediated Control of a Neutrophil-Dependent Murine Model of Rheumatoid Arthritis

Por Cremasco, Viviana, Graham, Daniel B., Novack, Deborah V., Swat, Wojciech, Faccio, Roberta
Publicado em 2008

ITAM Signaling by Vav Family Rho Guanine Nucleotide Exchange Factors Regulates Interstitial Transit Rates of Neutrophils In Vivo

Por Graham, Daniel B., Zinselmeyer, Bernd H., Mascarenhas, Francesca, Delgado, Ryan, Miller, Mark J., Swat, Wojciech
Publicado em 2009

Cell-Autonomous Control of IL-7 Response Revealed In a Novel Stage of Precursor B Cells

Por Sandoval, Gabriel J., Graham, Daniel B., Bhattacharya, Deepta, Sleckman, Barry P., Xavier, Ramnik J., Swat, Wojciech
Publicado em 2013

Polarity gene discs large homolog 1 regulates the generation of memory T cells

Por Gmyrek, Grzegorz B., Graham, Daniel B., Sandoval, Gabriel, Blaufuss, Gregory S., Akilesh, Holly M., Fujikawa, Keiko, Xavier, Ramnik J., Swat, Wojciech
Publicado em 2013

Simultaneous Pathway Activity Inference and Gene Expression Analysis Using RNA Sequencing

Por O'Connell, Daniel J., Kolde, Raivo, Sooknah, Matthew, Graham, Daniel B., Sundberg, Thomas B., Latorre, Isabel, Mikkelsen, Tarjei S., Xavier, Ramnik J.
Publicado no Cell Syst (2016)

Vav proteins control MyD88-dependent oxidative burst

Por Miletic, Ana V., Graham, Daniel B., Montgrain, Vivianne, Fujikawa, Keiko, Kloeppel, Tracie, Brim, Karry, Weaver, Brian, Schreiber, Robert, Xavier, Ramnik, Swat, Wojciech
Publicado em 2007

Dendritic Cells Utilize the Evolutionarily Conserved WASH and Retromer Complexes to Promote MHCII Recycling and Helper T Cell Priming

Por Graham, Daniel B., Osborne, Douglas G., Piotrowski, Joshua T., Gomez, Timothy S., Gmyrek, Grzegorz B., Akilesh, Holly M., Dani, Adish, Billadeau, Daniel D., Swat, Wojciech
Publicado em 2014

An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells

Por Graham, Daniel B., Stephenson, Linda M., Lam, Siu Kit, Brim, Karry, Lee, Hyang Mi, Bautista, Jhoanne, Gilfillan, Susan, Akilesh, Shreeram, Fujikawa, Keiko, Swat, Wojciech
Publicado em 2007

PKCδ Deficiency Perturbs Bone Homeostasis by Selective Uncoupling of Cathepsin K Secretion and Ruffled Border Formation in Osteoclasts

Por Cremasco, Viviana, Decker, Corinne E., Stumpo, Deborah, Blackshear, Perry J., Nakayama, Keiichi I., Nakayama, Keiko, Lupu, Traian S., Graham, Daniel B., Novack, Deborah V., Faccio, Roberta
Publicado em 2012

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation

Por Doench, John G., Hartenian, Ella, Graham, Daniel B., Tothova, Zuzana, Hegde, Mudra, Smith, Ian, Sullender, Meagan, Ebert, Benjamin L., Xavier, Ramnik J., Root, David E.
Publicado no Nat Biotechnol (2014)

DLGH1 Is a Negative Regulator of T-Lymphocyte Proliferation

Por Stephenson , Linda M., Sammut, Bénédicte, Graham, Daniel B., Chan-Wang, Joaquim, Brim, Karry L., Huett, Alan S., Miletic, Ana V., Kloeppel, Tracie, Landry, Aimee, Xavier, Ramnik, Swat, Wojciech
Publicado em 2007

Vav Links the T Cell Antigen Receptor to the Actin Cytoskeleton and T Cell Activation Independently of Intrinsic Guanine Nucleotide Exchange Activity

Por Miletic, Ana V., Graham, Daniel B., Sakata-Sogawa, Kumiko, Hiroshima, Michio, Hamann, Michael J., Cemerski, Saso, Kloeppel, Tracie, Billadeau, Daniel D., Kanagawa, Osami, Tokunaga, Makio, Swat, Wojciech
Publicado em 2009

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes

Por Stephenson, Linda M., Miller, Brian C., Ng, Aylwin, Eisenberg, Jason, Zhao, Zijiang, Cadwell, Ken, Graham, Daniel B., Mizushima, Noboru N., Xavier, Ramnik, Virgin, Herbert W., Swat, Wojciech
Publicado em 2009

Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCγ2 signaling axis in mice

Por Graham, Daniel B., Robertson, Charles M., Bautista, Jhoanne, Mascarenhas, Francesca, Diacovo, M. Julia, Montgrain, Vivianne, Lam, Siu Kit, Cremasco, Viviana, Dunne, W. Michael, Faccio, Roberta, Coopersmith, Craig M., Swat, Wojciech
Publicado em 2007

Loss of DAP12 and FcRγ Drives Exaggerated IL-12 Production and CD8(+) T Cell Response by CCR2(+) Mo-DCs

Por Gmyrek, Grzegorz B., Akilesh, Holly M., Graham, Daniel B., Fuchs, Anja, Yang, Lihua, Miller, Mark J., Sandoval, Gabriel J., Sheehan, Kathleen C. F., Schreiber, Robert D., Diamond, Michael S., Swat, Wojciech
Publicado em 2013

Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst

Por Graham, Daniel B., Becker, Christine E., Doan, Aivi, Goel, Gautam, Villablanca, Eduardo J., Knights, Dan, Mok, Amanda, Ng, Aylwin C.Y., Doench, John G., Root, David E., Clish, Clary B., Xavier, Ramnik J.
Publicado no Nat Commun (2015)

Nitric Oxide Engages an Anti-inflammatory Feedback Loop Mediated by Peroxiredoxin 5 in Phagocytes

Por Graham, Daniel B., Jasso, Guadalupe J., Mok, Amanda, Goel, Gautam, Ng, Aylwin C.Y., Kolde, Raivo, Varma, Mukund, Doench, John G., Root, David E., Clish, Clary B., Carr, Steven A., Xavier, Ramnik J.
Publicado no Cell Rep (2018)

Novel Mechanism of Tumor Suppression by Polarity Gene Discs Large 1 (DLG1) Revealed in a Murine Model of Pediatric B-ALL

Por Sandoval, Gabriel J., Graham, Daniel B., Gmyrek, Grzegorz B., Akilesh, Holly M., Fujikawa, Keiko, Sammut, Benedicte, Bhattacharya, Deepta, Srivatsan, Shuba, Kim, Alfred, Shaw, Andrey S., Yang-Iott, Katherine, Bassing, Craig H., Duncavage, Eric, Xavier, Ramnik J., Swat, Wojciech
Publicado em 2013