טוען...
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation
Components of the prokaryotic clustered regularly interspersed palindromic repeat (CRISPR) loci have recently been repurposed for use in mammalian cells(1–6). The Cas9 protein can be programmed with a single guide RNA (sgRNA) to generate site-specific DNA breaks, but there are few known rules govern...
שמור ב:
| הוצא לאור ב: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2014
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262738/ https://ncbi.nlm.nih.gov/pubmed/25184501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3026 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|