Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool

Por Donovan, Katherine F., Hegde, Mudra, Sullender, Meagan, Vaimberg, Emma W., Johannessen, Cory M., Root, David E., Doench, John G.
Publicado no PLoS One (2017)

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation

Por Doench, John G., Hartenian, Ella, Graham, Daniel B., Tothova, Zuzana, Hegde, Mudra, Smith, Ian, Sullender, Meagan, Ebert, Benjamin L., Xavier, Ramnik J., Root, David E.
Publicado no Nat Biotechnol (2014)

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

Por Doench, John G., Fusi, Nicolo, Sullender, Meagan, Hegde, Mudra, Vaimberg, Emma W., Donovan, Katherine F., Smith, Ian, Tothova, Zuzana, Wilen, Craig, Orchard, Robert, Virgin, Herbert W., Listgarten, Jennifer, Root, David E.
Publicado no Nat Biotechnol (2016)

Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens

Por Najm, Fadi J, Strand, Christine, Donovan, Katherine F, Hegde, Mudra, Sanson, Kendall R, Vaimberg, Emma W, Sullender, Meagan E, Hartenian, Ella, Kalani, Zohra, Fusi, Nicolo, Listgarten, Jennifer, Younger, Scott T, Bernstein, Bradley E, Root, David E, Doench, John G
Publicado no Nat Biotechnol (2017)

Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C.elegans

Por McShea, Molly A., Schmidt, Kristopher L., Dubuke, Michelle L., Baldiga, Christina E., Sullender, Meagan E., Reis, Andrea L., Zhang, Subaiou, O'Toole, Sean M., Jeffers, Mary C., Warden, Rachel M., Kenney, Allison H., Gosselin, Jennifer, Kuhlwein, Mark, Hashmi, Sana K., Stringham, Eve G., Ryder, Elizabeth F.
Publicado no Dev Biol (2012)