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ge-CRISPR - An integrated pipeline for the prediction and analysis of sgRNAs genome editing efficiency for CRISPR/Cas system

Genome editing by sgRNA a component of CRISPR/Cas system emerged as a preferred technology for genome editing in recent years. However, activity and stability of sgRNA in genome targeting is greatly influenced by its sequence features. In this endeavor, a few prediction tools have been developed to...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Kaur, Karambir, Gupta, Amit Kumar, Rajput, Akanksha, Kumar, Manoj
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007494/
https://ncbi.nlm.nih.gov/pubmed/27581337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30870
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