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Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes

Autophagy is implicated in many functions of mammalian cells such as organelle recycling, survival and differentiation, and is essential for the maintenance of T and B lymphocytes. Here, we demonstrate that autophagy is a constitutive process during T cell development. Deletion of the essential auto...

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Detalhes bibliográficos
Main Authors: Stephenson, Linda M., Miller, Brian C., Ng, Aylwin, Eisenberg, Jason, Zhao, Zijiang, Cadwell, Ken, Graham, Daniel B., Mizushima, Noboru N., Xavier, Ramnik, Virgin, Herbert W., Swat, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737142/
https://ncbi.nlm.nih.gov/pubmed/19276668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.5.5.8133
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