Vav proteins control MyD88-dependent oxidative burst

The importance of reactive oxygen intermediate (ROI) production in antimicrobial responses is demonstrated in human patients who suffer from chronic granulomatous disease (CGD) due to defective NADPH oxidase function. Exactly how bacterial products activating Toll-like receptors (TLRs) induce oxidat...

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Detalhes bibliográficos
Main Authors: Miletic, Ana V., Graham, Daniel B., Montgrain, Vivianne, Fujikawa, Keiko, Kloeppel, Tracie, Brim, Karry, Weaver, Brian, Schreiber, Robert, Xavier, Ramnik, Swat, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852252/
https://ncbi.nlm.nih.gov/pubmed/17158234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-033662
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